| Assignment | Titile/Topic Question |
| PICO # 1 | In an adult postoperative patient unable to take Heparin for DVT prophylaxis, does the use of ASA compared to anticoagulants like Argatroban or Apixaban result in comparable rates of venous thromboembolism and hemorrhagic complications? |
| PICO # 2 | In adults with spontaneous esophageal perforation (Boerhaave syndrome), does conservative/non-operative management compared with early surgical intervention improve survival and reduce complications? |
| PICO # 3 | In adults with uncomplicated appendicitis, does conservative treatment with antibiotics compared with appendectomy lead to similar treatment success and lower risks of complications? |
| PICO # 4 | In children with traumatic skin lacerations, does tissue adhesive compared to sutures result in similar cosmetic outcomes, infection rates, and wound healing times? |
| PICO # 5 | In febrile pediatric patients, does ibuprofen compared to acetaminophen result in greater fever reduction, improved comfort and symptom control? |
| PICO # 6 | In children with viral URI, does honey compared to OTC cough medications provide safer and better symptom relief? |
| Mini-CAT | In pediatric patients with suspected appendicitis, how does a staged imaging protocol (ultrasound followed by CT, if US findings are equivocal) compared to CT alone in terms of diagnostic accuracy? |
